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Multiple Autoimmune Syndrome (MAS), AutoInflammatory Disease and Inflammation
For a long time, people who suffered from the seemingly related disorders known as multiple autoimmune syndrome (MAS) and autoinflammatory disease were thought to be hypochondriacs or lazy when they complained to their doctors about their symptoms: skin rashes, chronic fatigue, joint pain, unexplained fevers, chest pain and abdominal pain just to name a few.
Now, doctors and researchers have organized patients and their symptoms into two primary and related groups:

• Those with multiple autoimmune syndrome
• Those with (what is now referred to as) autoinflammatory disease
While the two categories have distinct differences, they also have commonalities, the primary one being inflammation. With both types of conditions, the body’s immune system is “confused” and attacks itself.

Multiple Autoimmune Syndrome (MAS) occurs when a person has three or more autoimmune diseases simultaneously and one of them is a skin disorder such as psoriasis, scleroderma or vitiligo.

Autoinflammatory disease is also an autoimmune disorder, and comes under a number of different guises:

• Familial Mediterranean Fever (FMF)

• Behcet’s disease

• Neonatal Onset Multisystem Inflammatory Disease (NOMID)

• Tumor Necrosis Factor (TNF) receptor-associated periodic syndrome (TRAPS)

• Deficiency of the interleukin-1 (IL-1) receptor antagonist (DIRA)

These inflammatory diseases cause problems that range from skin rashes, soresabdominal pain and joint pain, unexplained fevers, inflamed blood vessels, adrenal insufficiency /fatigue, inflammation (chronic) is at the root of most human diseases and heart failure.

Chronic inflammation is commonly associated with each type of MAS. It is believed the inflammation encourages T-cellsv, intended to defend the immune system for a short-term assault, to stay “on” and attack the body instead. This causes tremendous damage in various areas of the body depending upon which system the T-cells falsely identify as a harmful invader. If the chronic inflammation is in the brain it can contribute to Alzheimer’s or Parkinson’s for example, in the circulation system, heart disease or stroke. If fat cells are chronically inflamed, it begins the process of type 2 diabetes. Inflammation in the gut leads to a host of painful skin disorders, joint diseases and bowel diseases including cancer. Genes become damaged and the immune system’s ability to correctly function is further compromised.

Add into this equation the many toxins present in our modern food chain and environment, plus high-risk behavior such as overeating, a diet high in carbohydrates and bad fats, lack of exercise, smoking, too much alcohol consumption and you have the unhealthy beginnings of MAS. However, there are actions you can take to reclaim your health.

The degree to which multiple autoimmune syndrome and autoinflammatory disease can be remediated, and chronic inflammatory response “turned off”, with lifestyle changes such as an anti-inflammatory diet, supplements and exercise has been area of intense study for several years.

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