How Does What is the Chemical Name for CAS 36265-41-5? Work?

Author: Vic

Oct. 18, 2024

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The Chemical Identity of CAS 36265-41-5

The Chemical Abstracts Service (CAS) number 36265-41-5 is associated with a specific chemical compound known as Clorgyline. Clorgyline is primarily recognized as a selective monoamine oxidase inhibitor (MAOI). This classification makes it significant in pharmacology, particularly in the treatment of depression and other mood disorders. Understanding the importance of the chemical name for CAS 36265-41-5 plays a vital role in the research and development of medications and therapeutic applications.

Structure and Composition

The chemical structure of Clorgyline allows it to effectively inhibit the activity of the monoamine oxidase enzyme. Its molecular formula is C10H12ClN. This formula indicates that Clorgyline contains ten carbon atoms, twelve hydrogen atoms, one chlorine atom, and one nitrogen atom. The structural integrity of the compound is crucial for its interaction with the enzyme, thereby influencing its efficacy as a therapeutic agent.

Mechanism of Action

Clorgyline functions by selectively inhibiting the monoamine oxidase A (MAO-A) enzyme, which is responsible for breaking down neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. By inhibiting this enzyme, Clorgyline increases the levels of these neurotransmitters, which can enhance mood and alleviate symptoms of depression. The selectivity of Clorgyline for MAO-A over MAO-B is crucial, as this specificity minimizes side effects associated with less selective MAO inhibitors.

Applications in Medicine

Given its properties and mechanism of action, Clorgyline is valuable in treating patients with depression, especially those who have not responded well to traditional antidepressants. Additionally, its use extends to anxiety disorders and certain other psychiatric conditions. The pharmacological significance of Clorgyline has led to ongoing research on its potential benefits and applications in various mental health contexts.

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Safety and Side Effects


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While Clorgyline has demonstrated effectiveness, it is essential to consider its safety profile. Common side effects may include headaches, insomnia, and gastrointestinal disturbances. More severe adverse effects can occur, especially when Clorgyline is consumed with tyramine-rich foods, leading to hypertensive crises. Effective patient education and monitoring are required to mitigate these risks, ensuring that individuals using Clorgyline experience beneficial outcomes without severe complications.

Research and Development

The landscape of depression treatment continues to evolve. Ongoing research regarding Clorgyline focuses on its long-term effects, optimal dosages, and broader applications in psychiatry. Studies aim to refine its therapeutic use and explore its effectiveness in combination with other treatments. Understanding the chemical attributes and physiological effects of Clorgyline contributes significantly to the medical community's knowledge, shaping approaches to treatment strategies for depression and related disorders.

Conclusion

In summary, understanding the chemical name associated with CAS 36265-41-5 is more than an academic exercise; it has real-world implications in pharmacology and mental health treatment. Clorgyline's selective action as a monoamine oxidase inhibitor offers promise for managing various mood disorders. As ongoing research sheds further light on its effects, healthcare professionals are better equipped to enhance patient care. For further inquiries or detailed information about Clorgyline, feel free to contact us.

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